REVIEW ON ANOGEISSUS LEIOCARPUS A POTENT AFRICAN TRADITIONAL DRUG. Article (PDF Available) in International Journal of Research in Pharmacy . Common Name: African Birch. Anogeissus leiocarpa. Close-up of the flowers. Photograph by: Marco Schmidt Creative Commons Attribution-Share Alike Abstract Despite the fact that Anogeissus leiocarpus has been in use for many decades in the treatment of many illnesses little is known about its phytochemistry.

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Inhibition of pyocyanin production was anogeissuw according to previously described procedures [ 27 ]. Due to its extensive arsenal of virulence factors and inherent resistance to antibiotics, Pseudomonas aeruginosa is a threat particularly in immunocompromised patients.

The reporter strains Chromobacterium violaceum CV and P. Leiocarps rats were sacrificed humanely by jugular decapitation 24 h after the last administration of the extract and blood samples collected.

The protocol employed met the guidelines of Good Laboratory Practice GLP regulations of World Health Organisation and also the guidelines governing handling of laboratory animals as stipulated by Bayero University animal research ethics committee as well as the principles of laboratory animal care.

The results of the liver enzymes and total and direct biluribin leiocaprus presented in Table 2. However, bacteria increasingly exhibit resistance against available antimicrobial drugs [ 1819 ]. Occurrence nature, food, other: Materials and Methods 2. Antioxidant Activity, Total Polyphenol, and Flavovoid Content Total polyphenol and total flavonoid were quantified from methanol extract of A.

Anogeissus leiocarpa

Group 1 was not administered with any extract. Antiprotozoal activity of saponins from Anogeissus leiocarpus Combretaceae. Table 1 presents the result of quantitative anogeissuus of phytochemicals present in the aqueous bark extract of the A.


Role of qnogeissus in the emergence of multiply resistant strains. Anti-quorum sensing QS activity of methanol extract from A. In anigeissus infusion or decoction form, the bark is used as a medicine for cough. The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa.

The powder is also used as vermifuges and decoction of the leaves for fumigation and washing Ibrahim et al. Stem bark of Anogeissus leiocarpus DC Guill.

Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa by south Florida plant extracts. Screening for antimicrobial anogiessus. Dimethyl sulfoxide DMSO was used as negative control. Antibacterial effect of the extracts of leaf, stem and root bark of Anogeissus leiocarpus on S. Antimicrobial Activity of certain Sudanese plants used in folkloric medicine. Recommendation for anogeissus leiocarpus bark extract flavor usage levels up to:.

Serum collected from anlgeissus blood samples at the end of the treatment was used to assay for alanine aminotransferase ALTaspartate aminotransferase AST as described by Reitman and Frankel using commercial reagent kits Randox Laboratories Limited, United Kindom.

It has a dense crown and often drooping branches. MIC minimum inhibitory concentration values on P. Asian Journal of Scientific Research Volume 6 4: Within the Combretaceae family, to which belongs A. Anogeisdus of administration of aqueous bark leicoarpus of A. Discussion Our in vitro investigations show that methanol extract from A. Quantitative Analysis of Violacein Production in C. The bark, when made as a powder, is used to relieve tooth ache on gums.

In vitro evaluation of the antioxidant potential, phenolic and flavonoid contents of the stem bark ethanol extract of Anogeissus leiocarpus.


Current status of burn wound pathophysiology. Anogeissuw activity of terpenoidal fractions from Anogeissus leiocarpus and Terminalia avicennioides against community acquired infections. The amount of total polyphenol was particularly high Cytotoxic activity of aqueous extracts of Anogeissus leiocarpus and Terminalia avicennioides root barks against Ehrlich ascites carcinoma cells.

anogeissus leiocarpus bark extract

In vitro inhibition of mycobacterium smegmatis atcc and a clinical isolate of mycobacterium tuberculosis by some nigerian medicinal plants. Botanical identity was assessed by Dr.

University of Ife Press, Ile-Ife, pp: African Medicinal Plants, Sofowora, A. Fluoroquinolone consumption and emerging resistance. Steroids were found to be Moreover, the antioxidant polyphenols evidenced are able to reduce the oxidative stress induced by pyocyanin. This strain is unable to produce quorum sensing auto inducers homoserine-lactones by itself, nor therefore the QS-related violacein, without an external supply of homoserine-lactone.

Helminthiasis, trypanosomiasis, malaria and dysenteric syndrome are treated by traditional practitioners using the bark, trunk, roots and leaves parts of A. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert’s syndrome.

Since phzthe biosynthesis genes of pyocyanin, is under the control of las and rhl QS systems [ 2930 ], the observed decrease in pyocyanin production is related to the downstreaming of the QS regulator gene rhlR.